Nicholas Hadaš

Washington University in St. Louis

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hadasn (at) wustl (dot) edu

I am a Bioinformatics Research Tech II in the Horani Lab, where we explore the complexities of genetic ciliopathies. I am also a Master of Science student in Biomedical Informatics (DBBS) at Washington University School of Medicine in St. Louis, where I research in the Fuhai Li AI lab.

My primary research interest is in developing deep learning frameworks to model cellular function and better understand disease pathogenesis. I create computational tools and employ machine learning to investigate disease mechanisms using biological and biomedical data.

I have previously researched at the National Research Council of Canada and completed my undergrad in Biochemistry + Bioinformatics at the University of Waterloo.

selected publications

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    Comparative Single-Cell Transcriptomics Uncovers Shared and Distinct Molecular Signatures in Cystic Fibrosis and Primary Ciliary Dyskinesia
    Nicholas Hadas, Huihui Xu, Wang K Twan, and 4 more authors
    bioRxiv, 2025
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    Machine Learning Analysis of Cilia-Driven Particle Transport Distinguishes Primary Ciliary Dyskinesia Cilia from Normal Cilia
    Nicholas Hadas, Huihui Xu, Shambhawee Neupane, and 3 more authors
    bioRxiv, 2025
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    OmniCellTOSG: The First Cell Text-Omic Signaling Graphs Dataset for Graph Language Foundation Modeling
    Heming Zhang, Tim Xu, Dekang Cao, and 20 more authors
    arXiv, 2025
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    Transcriptional analysis of primary ciliary dyskinesia airway cells reveals a dedicated cilia glutathione pathway
    Jeffrey R Koenitzer, Deepesh Kumar Gupta, Wang Kyaw Twan, and 11 more authors
    JCI Insight, 2024